Evaluation of Antimicrobial Activity of Root Extracts of Abitulon indicum

  • Aniel Kumar OWK Department of Botany, Andhra University, Visakhapatnam – 530 003 (A.P.)
  • Krishna Rao MORTHA Department of Botany, Andhra University, Visakhapatnam – 530 003 (A.P.)
  • Mutyala Naidu LAGUDU Department of Botany, Andhra University, Visakhapatnam – 530 003 (A.P.)
Keywords: alcohol extract; bioactive compounds; microorganisms; MIC

Abstract

Antimicrobial activity of Abitulon indicum roots was studied against seven pathogenic bacteria and three fungal strains by agar well diffusion method. Antimicrobial activity was recorded for hexane, chloroform, methanol, ethanol and aqueous extracts. Alcohol (ethanol and methanol) extracts exhibited the highest degree of antimicrobial activity compared to aqueous, chloroform and hexane extracts. Pseudomonas aeruginosa was turned out to be the most susceptible bacterium to the crude root chemical constituents, using the standard Tetracycline and Clotrimazole. Minimum inhibition concentration values of hexane, chloroform, methanol, ethanol and aqueous extracts were determined by the agar dilution method and ranged between 62.5 and 1,000 µg. The study suggested that the root extracts possess bioactive compounds with antimicrobial activity against the tested bacteria and fungi, revealing a significant scope to develop a novel broad spectrum of antimicrobial drug formulation from Abitulon indicum.

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Published
2015-06-21
How to Cite
OWK, A. K., MORTHA, K. R., & LAGUDU, M. N. (2015). Evaluation of Antimicrobial Activity of Root Extracts of Abitulon indicum. Notulae Scientia Biologicae, 7(2), 160-163. https://doi.org/10.15835/nsb729501
Section
Research articles