TY - JOUR AU - ADENIYI, Tiwalade Adeyemi AU - ADEONIPEKUN, Peter A. AU - OMOTAYO, Elizabeth A. PY - 2014/09/22 Y2 - 2024/03/28 TI - Investigating the Phytochemicals and Antimicrobial Properties of Three Sedge (Cyperaceae) Species JF - Notulae Scientia Biologicae JA - Not Sci Biol VL - 6 IS - 3 SE - Research articles DO - 10.15835/nsb639356 UR - https://notulaebiologicae.ro/index.php/nsb/article/view/9356 SP - 276-281 AB - <p style="text-align: justify;">In order to evaluate the medicinal value of notorious sedge weeds, three species:<em>Cyperus esculentus</em>, <em>Cyperus rotundus</em> and <em>Mariscus alternifolius</em> were investigated for their phytochemical constituents and antimicrobial properties. Preliminary qualitative phytochemical constituents and <em>in vitro</em> antimicrobial activities were evaluated against four fungi species<em>: Aspergillus niger</em>, <em>Aspergillus fumigatus</em>, <em>Penicillium chrysogenum</em> and <em>Candida albicans</em>, and three bacteria species: <em>Escherichia coli</em>,<em>Salmonella typhi</em> and <em>Staphylococcus aureus</em>. Two solvents, water and ethanol, were used to produce the extracts and were screened for their antimicrobial activity. Antimicrobial activity evaluation of the extracts against pathogens was carried out at 100 mg/ml concentration by Disc Diffusion method for fungi, Disc Diffusion and Agar Well Diffusion methods for bacteria. Observed activities were related to standard antibiotics, antifungal and antibacterial, which served as controls. Phytochemically, the plant extracts showed the presence of carbohydrates, flavonoids, ketose sugars, steroids, reducing sugars and tannins. The ethanolic extract of <em>C. rotundus</em> exhibited the highest activity against <em>A. niger</em>, <em>E. coli</em> and <em>S. aureus</em>. No extract was active against <em>C. albicans</em>. From these findings, it was concluded that<em> C. rotundus</em> is a potential source of bioactive compounds for new drugs upon isolation and purification for treating infections caused by these pathogens.</p> ER -