MicroRNA Implication in Cancer

  • Iker BADIOLA Innovative Technologies in Biological Systems (INNOPROT), Parque Tecnológico de Bizkaia Ed. 502-1º, 48160, Derio
Keywords: microRNA; cancer; metastasis; post-transcription; biomarkers

Abstract

MicroRNAs (miRNA) are a new class of posttranscriptional regulators. These small non-coding RNAs regulate the expression of target mRNA transcripts and are linked to several human disease such as Alzheimer, cancer or heart disease. But it has been the cancer disease which has experimented the major number of studies of miRNA linked to the disease progression. In the last years it has been reported the deregulation pattern of the miRNAs in malignant cells which have disrupted the control of the proliferation, differentiation or apoptosis. The evidence of the presence of specific miRNA deregulated in concrete cancer types has become the miRNAs like possible biomarkers and therapeutic targets. The specific miRNA patterns deregulated in concrete cancer cell types open new opportunities to the diagnosis and therapy.

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Author Biography

Iker BADIOLA, Innovative Technologies in Biological Systems (INNOPROT), Parque Tecnológico de Bizkaia Ed. 502-1º, 48160, Derio
Director of Product Development
Published
2010-03-09
How to Cite
BADIOLA, I. (2010). MicroRNA Implication in Cancer. Notulae Scientia Biologicae, 2(1), 07-13. https://doi.org/10.15835/nsb214566
Section
Review articles