A Natural Wonder Drug Helps to Prevent Cancer: Garlic Oil

  • Sankaran MIRUNALINI Annamalai University, Faculty of Science, Department of Biochemistry and Biotechnology, Tamil Nadu
  • Ganesan DHAMODHARAN Annamalai University, Faculty of Science, Department of Biochemistry and Biotechnology, Tamil Nadu
  • Kandhan KARTHISHWARAN Annamalai University, Faculty of Science, Department of Biochemistry and Biotechnology, Tamil Nadu
Keywords: garlic oil; oxidative stress; antioxidants; anticancer mechanism; free radicals

Abstract

Garlic is one of the oldest and popular spices in the World that also contain very good nutritional value. Garlic has a wide spectrum of actions not only is it antibacterial, antiviral, antifungal and antiprotozoan but it also has beneficial effects on the cardiovascular and immune systems. They contain unique oil which is very easily digested and is stable to oxidative stress and for this reasons they are useful and healthy for consumption. Several epidemiological and experimental studies suggest that garlic oil has been thought to bring about its anticarcinogenic effect and other pharmacological properties through a number of mechanisms, such as the scavenging of radicals, increasing glutathione levels, increasing the activities of enzymes such as glutathione S transferase, catalase, incubation of cytochrome p450 2E1, DNA repair mechanisms, prevention of chromosomal damage etc. Future research should standardize the dosage of garlic and type. Several hypotheses suggest that the anticancer mechanism may be due to DNA repair mechanism, prevention of chromosomal damage, antiproliferative effect and alteration of the cell cycle. Garlic and garlic oil should be considered as one of the most valuable food for good quality of life in general.

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Published
2010-03-09
How to Cite
MIRUNALINI, S., DHAMODHARAN, G., & KARTHISHWARAN, K. (2010). A Natural Wonder Drug Helps to Prevent Cancer: Garlic Oil. Notulae Scientia Biologicae, 2(1), 14-19. https://doi.org/10.15835/nsb213593
Section
Review articles