Helosciadium crassipes Koch (Apiaceae) extracts as natural sunscreen and preservative additives


  • El-Hani MAKHLOUFI University Constantine 1, Faculty of Exact Sciences, Unit of the Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analysis, Constantine 25000; University Mohamed Boudiaf of M’sila, Faculty of Technology, Base Common ST, BP 166 M’sila 28000 (DZ)
  • Mostefa LEFAHAL University Constantine 1, Faculty of Exact Sciences, Unit of the Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analysis, Constantine 25000; University Salah Boubnider Constantine 3, Faculty of Medicine, BP 'B' 72Ali Mendjeli Nouvelle Ville 25000 Constantine (DZ)
  • Radia AYAD University Constantine 1, Faculty of Exact Sciences, Unit of the Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analysis, Constantine 25000; University of Jijel, Faculty of Exact Sciences and Informatics, Department of Chemistry, Laboratory of Phytochemistry and Pharmacology, BP 98Ouled Aissa, 18000 Jijel (DZ)
  • Yavuz S. CAKMAK Aksaray University, Faculty of Science and Arts, Department of Biotechnology and Molecular Biology, Aksaray (TR)
  • Gema NIETO University of Murcia, Faculty of Veterinary Sciences, Department of Food Technology, Food Science and Nutrition, Regional Campus of International Excellence “Campus Mare Nostrum”, Espinardo, 30071 Murcia (ES)
  • Salah AKKAL University Constantine 1, Faculty of Exact Sciences, Unit of the Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analysis, Constantine 25000 (DZ)




Apiaceae, critical wavelength, HPLC, photoprotective activity, SPF, UVA/UVB


Recently, ingredients derived from natural sources have gained increasing interest in the cosmetic field due to their low toxicity. Therefore, this study was designed to explore the cosmetic potential of Helosciadium crassipes Koch (Apiaceae) species growing in Algeria as a promising natural preservative and broad-spectrum UV protection additive. In our study, the in-vitro antioxidant effect was assessed via DPPH radical scavenging and total antioxidant capacity by phosphomolybdenum method (TAC), while the protection against UVB radiation was evaluated according to the sun protection factor (SPF) by using UV spectroscopic technic at wavelengths ranging from 290 to 320 nm and Mansur’s equation, for the photoprotective effect against long-wavelength UVA, UVA/UVB and critical wavelength (λc) parameters were evaluated. The outcomes showed that among the tested extracts, the methanolic extract (MeOH) contains high levels of phenolics and flavonoids, and possesses a significant antioxidant effect, particularly in DPPH radical scavenging assay. Similarly, this last one exhibited high photoprotective activity in UVB and UVA ranges. The gathered results reveal the possibility of using this extract as a good natural additive to be incorporated into cosmetic formulations as a broad-spectrum UV protection candidate and as a preservative agent.


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How to Cite

MAKHLOUFI, E.-H., LEFAHAL, M., AYAD, R., CAKMAK, Y. S., NIETO, G., & AKKAL, S. (2023). Helosciadium crassipes Koch (Apiaceae) extracts as natural sunscreen and preservative additives. Notulae Scientia Biologicae, 15(4), 11639. https://doi.org/10.55779/nsb15411639



Research articles
DOI: 10.55779/nsb15411639