Incidence of Common and Rare Cancers in Ilorin, Nigeria

Authors

  • Abass T. ANIFOWOSHE University of Ilorin, Faculty of Life Sciences, Department of Zoology, Cell Biology and Genetics Unit, Ilorin (NG)
  • Olubukola A. OWOLODUN University of Ilorin, Faculty of Life Sciences, Department of Zoology, Cell Biology and Genetics Unit, Ilorin (NG)
  • Bashirudeen O. OYINLOLA University of Ilorin, Faculty of Life Sciences, Department of Zoology, Cell Biology and Genetics Unit, Ilorin (NG)
  • Kazeem ABDULGANIYU University of Ilorin, Faculty of Life Sciences, Department of Zoology, Cell Biology and Genetics Unit, Ilorin (NG)
  • Robiat D. YUSUF University of Ilorin, Faculty of Life Sciences, Department of Zoology, Cell Biology and Genetics Unit, Ilorin (NG)
  • Oyinkansola A. OREDEIN University of Ilorin, Faculty of Life Sciences, Department of Zoology, Cell Biology and Genetics Unit, Ilorin
  • Oluyinka A. IYIOLA University of Ilorin, Faculty of Life Sciences, Department of Zoology, Cell Biology and Genetics Unit, Ilorin (NG)

DOI:

https://doi.org/10.15835/nsb10410263

Keywords:

common cancer; Ilorin; incidence; Nigeria; rare cancer

Abstract

Cancer is a public health problem worldwide, affecting all categories of persons. It is the second common cause of death in developed countries and among the three leading causes of death in developing countries. Due to its genetics and medical importance, study on its incidence is germane. In the present study, 74 different cancers of 2,246 (n = 891 male and n = 1355 female) cancer patients within the age of 1-105 in Nigeria were retrospectively reviewed using the data from University of Ilorin Teaching Hospital (UITH). The overall profile of the categories showed the leading position of breast cancer, followed by cancer of the digestive system (32.29% and 19.67%, respectively), while Kaposi sarcoma, endocrine system and brain cancers were among the rare or least recorded (<1.0% incidence rate). Furthermore, the trend showed a high prevalence during 2011 and 2015 (>13% and >11%) than any other year within the study, while the lowest incidence was recorded in 2016 (<6%). Predisposing factors like tumorigenesis, immune system, biological stressors as well as gene-environment interaction and low life expectancy could influence the risk of different groups of cancer. Therefore, future investigations should be targeted on risk factors related to those considered rare so as to provide useful information about possible signs and symptoms for diagnosis before it escalate.

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References

Adebamowo CA, Adekunle OO (1999). Case control study of epidemiological risk factors for breast cancer in Nigeria. British Journal of Surgery 86(5):665-668.

Akinwande O, Ogundiran T, Akarolo SA, Mamadu I, Dakum P, Blattner W, Adebamowo C (2009). Challenges in treating malignancies in HIV in Nigeria. Current Opinion in Oncology 21(5):455.

Ananya MD (2012). Cancer Classification. News-Medical. Retrieved 2017 September 20 from http:// www. Newsmedical .net/health/Cancer-Classification.aspx pp 1-3.

Bah E, Parkin DM, Hall AJ, Jack AD, Whittle H (2001). Cancer in the Gambia: 1988-97. British Journal of Cancer 84(9):1207.

Bah E, Sam O, Whittle H, Ramanakumar A, Sankaranarayanan R (2011). Cancer survival in the Gambia, 1993-1997. IARC Scientific Publication 162:97-100.

de Kok IM, van Lenthe FJ, Avendano M, Louwman M, Coebergh JW, Mackenbach JP (2008). Childhood social class and cancer incidence: results of the globe study. Social Science & Medicine 66(5):1131-1139.

Dreiher J, Novack V, Barachana M, Yerushalmi R, Lugassy G, Shpilberg O (2005). Non-Hodgkin's lymphoma and residential proximity to toxic industrial waste in southern Israel. Haematologica 90(12):1709-1710.

Durosinmi MA (2008). Cancer control in an economically disadvantaged setting. Nigeria. INCTR Newsletter. Retrieved 2008 May 19 from www.inctr.org/publications/2004_v05-n01_s02.shtml.

Faggiano F, Partanen T, Kogevinas M, Boffetta P (1997). Socioeconomic differences in cancer incidence and mortality. IARC Scientific Publications (138):65-176.

Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM (2008). Cancer incidence, and mortality Worldwide. GLOBOCAN 2008.

Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. International Journal of Cancer 127(12):2893-2917.

Frimpong-Boateng K (2010). Infectious disease and cancer in Africa - A medical and demographical reality. A Keynote Lecture presented at the “Global Health and Molecular Medicine: Our Common Future”, Hannover. Retrieved 2017 October 23 from http: //www. ourcommonfuture.de.

Fritz A, Percy CL, Jack A, Shanmugaratnam K, Sobin L, Parkin DM (2000). International Classification of Diseases for Oncology. 3rd ed. (ICD-O-3). Geneva: World Health Organization.

Galea S, Nandi A, Vlahov D (2004). The social epidemiology of substance use. Epidemiologic Reviews 26(1):36-52.

Galobardes B, Shaw M, Lawlor DA, Lynch JW, Smith GD (2006). Indicators of socioeconomic position (part 1). Journal of Epidemiology & Community Health 60(1):7-12.

Globocan (2008). Country fast status-Nigeria. Retrieved 2011 May 23 from http://globocan.iarc.fr/factsheets/populations/ factsheet.asp?uno= 566.

Goldberg MS, Siemiatyck J, Dewar R, Désy M, Riberdy H (1999). Risks of developing cancer relative to living near a municipal solid waste landfill site in Montreal, Quebec, Canada. Archives of Environmental Health: An International Journal 54(4):291-296.

Greenlee RT, Goodman MT, Lynch CF, Platz CE, Havener LA, Howe HL (2010). The occurrence of rare cancers U. S. adults, 1995-2004. Public Health Reports 125:28-43

Gundrum JD, Go RS (2012). Cancer in the oldest old in the United States: current statistics and projections. Journal of Geriatric Oncology 3(4):299-306.

Hanson HA, Smith KR, Stroup AM, Harrell CJ (2015). An age-period-cohort analysis of cancer incidence among the oldest old, Utah 1973-2002. Population Studies 69(1):7-22.

Hiatt HH, Watson JD, Winsten JA (1977). Origins of human cancer. Book A. Incidence of cancer in humans; Book B. Mechanisms of carcinogenesis; Book C. Human risk assessment. Cold Spring Harbor Laboratory, Box 100, Cold Spring Harbor, NY 11724, USA.

Ikawo OE (2013). A Literature review on cancer in Nigeria. Department of biochemistry, college of medicine, University of Lagos. Retrieved 2017 October 25 from http: //www. academia.edu /3310884 /Cancer _In_Nigeria.

Irabor DO (2011). Colorectal carcinoma: Why is there a lower incidence in Nigerians when compared to Caucasians? Journal of Cancer Epidemiology doi:10.1155/2011/675154.

Jedy-Agba E, Curado MP, Ogunbiyi O, Oga E, Fabowale T, et al., Osinubi P (2013). Cancer incidence in Nigeria: a report from population-based cancer registries. Cancer Epidemiology 36(5):e271-278.

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ (2009). Cancer statistics. CA: a Cancer Journal for Clinicians 59(4):225-249.

Kanavos P (2006). The rising burden of cancer in the developing world. Annals of Oncology 17(8):viii 15-viii 23.

Laberge RM, Sun Y, Orjalo AV, Patil CK, Freund A, et al., Limbad C (2015). MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nature Cell Biology 17(8):1049.

Lambo EO (2007). Press release on state of health in Nigeria. Retrieved 2017 Aug 28.

Malcolm RA (2001). Cancer. In: Encyclopedia of Life Sciences. Nature Publishing Group, Imperial College School of Medicine. London, UK pp 420-428.

Menvielle G, Boshuizen H, Kunst AE, Vineis P, Dalton SO et al., Raaschou-Nielsen O (2010). Occupational exposures contribute to educational inequalities in lung cancer incidence among men: Evidence from the EPIC prospective cohort study. International Journal of Cancer 126(8):1928-1935.

Merletti F, Galassi C, Spadea T (2011). The socioeconomic determinants of cancer. Environmental Health. Vol. 10, No. 1, pp S7. BioMed Central.

Nolen SC, Evans MA, Fischer A, Corrada MM, Kawas CH, Bota DA (2017). Cancer- Incidence, prevalence and mortality in the oldest old. A comprehensive review. Mechanism of Ageing and Development 164:113-126.

Ogunbiyi JO, Shittu OB (1999). Increased incidence of prostate cancer in Nigerians. Journal of the National Medical Association 91(3):159.

Ogundiran TO, Huo D, Adenipekun A, Campbell O, Oyesegun R, et al., Olopade OI (2010). Case-control study of body size and breast cancer risk in Nigerian women. American Journal of Epidemiology 172(6):682-690.

Okobia MN (2003). Cancer care in Sub-Saharan Africa-urgent need for population-based cancer registries. Ethiopian Journal of Health Development 17(2):89-98.

Okobia MN, Aligbe JU (2005). Pattern of malignant diseases at the University of Benin Teaching Hospital. Tropical Doctor 35(2):91-92.

Olusegun O (2014). Spatial and socio-demographic disparities of cancer morbidity in Nigeria: Patterns and factors. Malaysian Journal of Society and Space 10(1):25-35.

Parkin DM, Wabinga H, Nambooze S, Wabwire-Mangen F (1999). AIDS-related cancers in Africa: maturation of the epidemic in Uganda. Aids 13(18):2563-70.

Piras F, Piga M, De Montis A, Zannou AR, Minerba L, et al., Sirigu P (2011). Prevalence of human papillomavirus infection in women in Benin, West Africa. Virology Journal 8(1):514.

Ries LG, Melbert D, Krapcho M, Mariotto A, Miller BA, Feuer EJ (2008). SEER cancer statistics review, 1975-2004. National Cancer Institute. Retrieved 2017 September 25 from http: //seer.cancer.gov/csr/1975_2004.

Sitas F, Pacella-Norman R, Carrara H, Patel M, Ruff P, et al., Connor M (2000). The spectrum of HIV-1 related cancers in South Africa. International Journal of Cancer 88(3):489-492.

Sylla BS, Wild CP (2012). A million africans a year dying from cancer by 2030: what can cancer research and control offer to the continent? International Journal of Cancer 130(2):245-250.

Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A (2015). Global cancer statistics, 2012. CA Cancer Journal of Clinicians 65(2):87-108.

WHEDA-Nigeria (2004). The women’s health and economic development association Newsletter. Retrieved 2017 November 25 from https://www.healthresearchweb.org/en/nigeria/cso_4367

WHO (2005). Global Action on Cancer-Update Version, Global Cancer Control pp 1-22.

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Published

2018-12-21

How to Cite

ANIFOWOSHE, A. T., OWOLODUN, O. A., OYINLOLA, B. O., ABDULGANIYU, K., YUSUF, R. D., OREDEIN, O. A., & IYIOLA, O. A. (2018). Incidence of Common and Rare Cancers in Ilorin, Nigeria. Notulae Scientia Biologicae, 10(4), 453–459. https://doi.org/10.15835/nsb10410263

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Section

Research articles
CITATION
DOI: 10.15835/nsb10410263

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